Collagen biostimulators have become increasingly popular in Brazil, especially in the field of facial harmonization. They offer a non-invasive alternative to rejuvenate the skin, improve firmness, and stimulate natural collagen production.
These products are mainly used to combat signs of aging, such as sagging and wrinkles, providing long-lasting and natural results. In this article, we explore the eight best collagen biostimulators sold in Brazil in 2024.
1. Sculptra®: The Pioneer in Biostimulation
Sculptra® is one of the most well-known and widely used collagen biostimulators worldwide. Based on poly-L-lactic acid (PLLA), it was launched in Europe in 1999 and in the United States in 2004. Sculptra® works by gradually stimulating collagen production over time, improving skin appearance, increasing firmness, and enhancing elasticity.
One of Sculptra®’s standout features is its long-lasting effect, with results that can last up to two years. However, due to the irregular shape of its particles, it requires a careful application technique to avoid the formation of nodules and granulomas.
2. Radiesse®: Dual Function of Filler and Biostimulation
Radiesse® is a widely used injectable collagen biostimulator made from calcium hydroxyapatite (CaHA). In addition to acting as a dermal filler, providing immediate volume, it also stimulates long-term natural collagen production. The calcium hydroxyapatite microspheres are biodegradable and safe, with visible results lasting up to a year or more.
A key advantage of Radiesse® is its ability to provide immediate correction, making it ideal for patients seeking quick results combined with long-lasting effects.
3. Aesthefill®: The New Generation of Biostimulators
Aesthefill® is a relatively new biostimulator in the Brazilian market, approved by ANVISA in 2021. Like Sculptra®, it is based on poly-D,L-lactic acid (PDLLA) but has some important differences. Aesthefill® uses spherical and porous particles, reducing the risk of clumping and allowing applications in more delicate areas, such as the forehead and periorbital region.
Another benefit of Aesthefill® is its faster absorption by the body, offering greater safety in terms of adverse reactions such as granulomas and inflammatory responses. Although it is a new product, it has shown promising results and is gaining popularity in the facial harmonization market.
4. Ellansé®: Personalized Collagen Stimulation
Ellansé® is a unique type of collagen biostimulator composed of polycaprolactone (PCL). It is designed to offer customized results, ranging from one to four years, depending on the chosen formula. This means patients can select a treatment that provides short- or long-term effects based on their individual needs.
Ellansé® is known for its versatility and effectiveness in both biostimulation and dermal filling.
5. Eleva®: High-Efficiency Biostimulation
Eleva® is another emerging biostimulator in the market, based on an innovative combination of poly-L-lactic acid (PLLA) and calcium hydroxyapatite (CaHA). This combination provides both immediate volumizing effects and prolonged biostimulation, making Eleva® an effective choice for improving skin quality and combating facial sagging.
Its results last around two years, and the product has stood out for its high patient satisfaction due to its natural and long-lasting effects.
6. Lanluma®: Body Biostimulation
Lanluma® is a biostimulator specifically designed for body areas such as the buttocks and thighs, but it can also be used on the face. It utilizes poly-L-lactic acid (PLLA) to stimulate collagen production and improve skin firmness, particularly in areas with greater sagging.
Lanluma® has gained popularity due to its effectiveness in body biostimulation, offering a less invasive alternative to surgical procedures for enhancing and defining body contours.
7. Hyperhid®: Innovation in Hyperhidrosis and Biostimulation
Although Hyperhid® is best known for treating hyperhidrosis (excessive sweating), it also acts as a collagen biostimulator in specific body areas. The product combines substances that not only reduce sweat production but also stimulate collagen, improving skin firmness and elasticity in treated areas.
8. Rennova®: A Versatile and Safe Option
Rennova® is a collagen biostimulator that offers an affordable and safe alternative for patients looking to improve skin appearance without undergoing invasive procedures. Composed of polycaprolactone (PCL), it has been shown to be effective in enhancing skin texture and firmness, with long-lasting results of up to two years.
This product is ideal for those seeking an accessible and effective treatment with a low risk of side effects.
Collagen biostimulators are revolutionizing facial and body aesthetics, offering natural and long-lasting results without the need for invasive surgical procedures. With various options on the market—from well-established ones like Sculptra® and Radiesse® to newer and more innovative products like Aesthefill® and Eleva®—patients can choose the treatment that best suits their individual needs.
These products not only enhance skin appearance but also naturally stimulate collagen production, providing gradual and sustainable rejuvenation. Whether for improving facial sagging, defining body contours, or simply revitalizing the skin, collagen biostimulators are an excellent choice for those seeking natural and long-lasting results.
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Clínica de Pele is a traditional and specialized dermatological clinic in Rio de Janeiro for over 60 years, since 1969.
Dr. Szerman has over 20 years of experience and teaches other doctors.
